STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSZCathepsin Z; Belongs to the peptidase C1 family. (303 aa)    
Predicted Functional Partners:
BCL2L1
Bcl-2-like protein 1 isoform 1.
     
 0.922
BID
BH3 interacting domain death agonist.
   
 
 0.906
BCL2
BCL2 apoptosis regulator.
     
 0.904
AGT
Angiotensinogen preproprotein; Belongs to the serpin family.
    
 0.875
LGMN
Legumain preproprotein.
   
 
 0.826
DNASE2
Deoxyribonuclease 2, lysosomal.
   
 
 0.765
CTSD
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.759
CTSF
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.752
BIRC5
Baculoviral IAP repeat-containing protein 5 isoform 1.
     
 0.714
CD68
CD68 molecule.
   
 
 0.711
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (48%) [HD]