Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (421 aa)    
Predicted Functional Partners:
PRKACB
cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily.
 
 
 0.998
PRKAR2A
Protein kinase cAMP-dependent type II regulatory subunit alpha.
  
0.995
PRKACG
cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
 
 
 0.990
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.
 
 
 0.990
PRKAR1B
Cyclic nucleotide-binding domain-containing protein.
  
 
0.985
PRKAR1A
Protein kinase cAMP-dependent type I regulatory subunit alpha.
  
 
0.983
AKAP14
A-kinase anchoring protein 14.
   
  0.974
PRKX
Uncharacterized protein; Belongs to the protein kinase superfamily.
 
 
 0.971
LOC106992273
Serine/threonine-protein kinase PRKX; Belongs to the protein kinase superfamily.
 
 
 0.971
AKAP5
A-kinase anchoring protein 5.
    
 0.955
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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