Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PGAM5Serine/threonine-protein phosphatase PGAM5, mitochondrial isoform 1. (289 aa)    
Predicted Functional Partners:
FUNDC1-2
FUN14 domain-containing protein 1.
    
 0.991
DNM1L
Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 0.952
MLKL
Mixed lineage kinase domain like pseudokinase.
    
 0.948
KEAP1
Kelch like ECH associated protein 1.
    
 
 0.945
BCL2L1
Bcl-2-like protein 1 isoform 1.
    
 0.929
FUNDC1
FUN14 domain-containing protein 1.
    
 0.927
PINK1
Serine/threonine-protein kinase PINK1, mitochondrial.
    
 
 0.871
BPGM
Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
      
 0.832
PHB2
Prohibitin.
   
 
 0.805
PARL
Rhomboid domain-containing protein.
      
 0.773
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.