CD84 protein (Macaca mulatta) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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[Homology]

Score

CD84

CD84 molecule. (345 aa)

Predicted Functional Partners:

SH2D1A

0.930

SH2D1B

0.919

CD244

0.825

CD2

0.809

CD48

0.748

LY9

0.672

CD58

0.662

ICOS

0.522

FANCM

0.510

SLAMF1

0.508

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD2	CD244	ENSMMUP00000065491	ENSMMUP00000022806	T-cell surface antigen CD2.	CD244 molecule.	0.557
CD2	CD48	ENSMMUP00000065491	ENSMMUP00000063275	T-cell surface antigen CD2.	CD48 molecule.	0.845
CD2	CD58	ENSMMUP00000065491	ENSMMUP00000010678	T-cell surface antigen CD2.	Uncharacterized protein.	0.999
CD2	CD84	ENSMMUP00000065491	ENSMMUP00000020294	T-cell surface antigen CD2.	CD84 molecule.	0.809
CD2	ICOS	ENSMMUP00000065491	ENSMMUP00000042779	T-cell surface antigen CD2.	Inducible T-cell costimulator.	0.624
CD2	LY9	ENSMMUP00000065491	ENSMMUP00000038573	T-cell surface antigen CD2.	Uncharacterized protein.	0.475
CD2	SH2D1A	ENSMMUP00000065491	ENSMMUP00000009960	T-cell surface antigen CD2.	SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2. However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1. Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions. Ca [...]	0.579
CD2	SH2D1B	ENSMMUP00000065491	ENSMMUP00000011156	T-cell surface antigen CD2.	SH2 domain containing 1B.	0.488
CD2	SLAMF1	ENSMMUP00000065491	ENSMMUP00000020773	T-cell surface antigen CD2.	Signaling lymphocytic activation molecule family member 1.	0.608
CD244	CD2	ENSMMUP00000022806	ENSMMUP00000065491	CD244 molecule.	T-cell surface antigen CD2.	0.557
CD244	CD48	ENSMMUP00000022806	ENSMMUP00000063275	CD244 molecule.	CD48 molecule.	0.999
CD244	CD58	ENSMMUP00000022806	ENSMMUP00000010678	CD244 molecule.	Uncharacterized protein.	0.426
CD244	CD84	ENSMMUP00000022806	ENSMMUP00000020294	CD244 molecule.	CD84 molecule.	0.825
CD244	FANCM	ENSMMUP00000022806	ENSMMUP00000021700	CD244 molecule.	FA complementation group M.	0.510
CD244	ICOS	ENSMMUP00000022806	ENSMMUP00000042779	CD244 molecule.	Inducible T-cell costimulator.	0.445
CD244	LY9	ENSMMUP00000022806	ENSMMUP00000038573	CD244 molecule.	Uncharacterized protein.	0.505
CD244	SH2D1A	ENSMMUP00000022806	ENSMMUP00000009960	CD244 molecule.	SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2. However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1. Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions. Ca [...]	0.995
CD244	SH2D1B	ENSMMUP00000022806	ENSMMUP00000011156	CD244 molecule.	SH2 domain containing 1B.	0.985
CD48	CD2	ENSMMUP00000063275	ENSMMUP00000065491	CD48 molecule.	T-cell surface antigen CD2.	0.845
CD48	CD244	ENSMMUP00000063275	ENSMMUP00000022806	CD48 molecule.	CD244 molecule.	0.999