STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UNC13AUnc-13 homolog A. (1677 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
    
 0.998
UNC13C
Unc-13 homolog C.
  
  
 
0.901
RIMS1
Regulating synaptic membrane exocytosis 1.
    
 0.866
STXBP1
Syntaxin-binding protein 1 isoform a; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.743
SNAP25
Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. Belongs to the SNAP-25 family.
   
 0.739
RAB3B
RAB3B, member RAS oncogene family.
   
 
 0.704
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 
 0.694
LOC114675624
Uncharacterized protein; Belongs to the MAGUK family.
   
 
 0.694
SYT1
Synaptotagmin 1.
   
 
 0.693
RIMS3
Regulating synaptic membrane exocytosis protein 3.
    
 0.673
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.