Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
STYK1Tyrosine-protein kinase STYK1. (422 aa)    
Predicted Functional Partners:
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component.
   
  
 0.860
RASAL2
RAS protein activator like 2.
   
 0.823
ERBB2
Receptor protein-tyrosine kinase.
    
 0.677
CDK2AP1
Cyclin dependent kinase 2 associated protein 1.
      
 0.663
SSBP2
Single-stranded DNA-binding protein 2.
      
 0.637
RSF1
Remodeling and spacing factor 1.
   
 
 0.607
MTDH
Metadherin.
   
  
 0.603
RBMS3
RNA binding motif single stranded interacting protein 3.
      
 0.584
BCAT1
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
      
 0.582
LOC703700
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
0.519
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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