Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIOTrio Rho guanine nucleotide exchange factor. (3093 aa)    
Predicted Functional Partners:
RHOA
Ras homolog family member A.
    
 0.841
RAC3
Ras-related C3 botulinum toxin substrate 3.
    
 0.811
RAC1
Uncharacterized protein.
    
 0.811
NUDCD1
NudC domain-containing protein 1 isoform 1.
    
 
 0.729
RHOJ
Rho-related GTP-binding protein RhoJ.
    
 0.725
RHOG
Rho-related GTP-binding protein RhoG.
    
 0.717
RAC2
Ras-related C3 botulinum toxin substrate 2.
    
 0.716
ENSMMUP00000069310
Uncharacterized protein.
    
 0.716
RHOBTB2
Rho related BTB domain containing 2.
    
 0.686
RHOBTB1
Rho-related BTB domain-containing protein 1.
    
 0.686
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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