REV1 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

REV1

DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1285 aa)

Predicted Functional Partners:

REV3L

0.996

MAD2L2

0.993

POLH

0.984

PCNA

0.973

POLI

0.960

POLK

0.958

POLD3

0.913

UBB

0.901

UBA52

0.889

WRN

0.856

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAD2L2	PCNA	ENSMMUP00000040604	ENSMMUP00000062455	Mitotic arrest deficient 2 like 2.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.865
MAD2L2	POLD3	ENSMMUP00000040604	ENSMMUP00000027170	Mitotic arrest deficient 2 like 2.	DNA polymerase delta subunit 3.	0.849
MAD2L2	POLH	ENSMMUP00000040604	ENSMMUP00000011676	Mitotic arrest deficient 2 like 2.	DNA polymerase eta.	0.916
MAD2L2	POLI	ENSMMUP00000040604	ENSMMUP00000041213	Mitotic arrest deficient 2 like 2.	DNA polymerase iota.	0.906
MAD2L2	POLK	ENSMMUP00000040604	ENSMMUP00000034468	Mitotic arrest deficient 2 like 2.	DNA polymerase kappa.	0.897
MAD2L2	REV1	ENSMMUP00000040604	ENSMMUP00000066793	Mitotic arrest deficient 2 like 2.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.993
MAD2L2	REV3L	ENSMMUP00000040604	ENSMMUP00000028357	Mitotic arrest deficient 2 like 2.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.997
MAD2L2	UBB	ENSMMUP00000040604	ENSMMUP00000050420	Mitotic arrest deficient 2 like 2.	Uncharacterized protein.	0.517
MAD2L2	WRN	ENSMMUP00000040604	ENSMMUP00000029828	Mitotic arrest deficient 2 like 2.	WRN RecQ like helicase.	0.446
PCNA	MAD2L2	ENSMMUP00000062455	ENSMMUP00000040604	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Mitotic arrest deficient 2 like 2.	0.865
PCNA	POLD3	ENSMMUP00000062455	ENSMMUP00000027170	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase delta subunit 3.	0.971
PCNA	POLH	ENSMMUP00000062455	ENSMMUP00000011676	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase eta.	0.991
PCNA	POLI	ENSMMUP00000062455	ENSMMUP00000041213	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase iota.	0.959
PCNA	POLK	ENSMMUP00000062455	ENSMMUP00000034468	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase kappa.	0.957
PCNA	REV1	ENSMMUP00000062455	ENSMMUP00000066793	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.973
PCNA	REV3L	ENSMMUP00000062455	ENSMMUP00000028357	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.958
PCNA	UBA52	ENSMMUP00000062455	ENSMMUP00000021162	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin-60S ribosomal protein L40.	0.934
PCNA	UBB	ENSMMUP00000062455	ENSMMUP00000050420	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.870
PCNA	WRN	ENSMMUP00000062455	ENSMMUP00000029828	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	WRN RecQ like helicase.	0.990
POLD3	MAD2L2	ENSMMUP00000027170	ENSMMUP00000040604	DNA polymerase delta subunit 3.	Mitotic arrest deficient 2 like 2.	0.849

page 1 of 6

Server load: medium (54%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About