Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PWP1PWP1 homolog, endonuclein. (511 aa)    
Predicted Functional Partners:
BRIX1
Brix domain-containing protein.
   
 
 0.963
EBNA1BP2
EBNA1 binding protein 2.
   
 
 0.956
NOC2L
NOC2 like nucleolar associated transcriptional repressor.
   
 
 0.949
RPF2
Ribosome production factor 2 homolog.
   
 
 0.944
RSL1D1
Ribosomal L1 domain containing 1.
   
 
 0.938
GTPBP4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.937
PES1
Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.
   
 
 0.924
PDCD11
Programmed cell death 11.
   
 
 0.906
GRWD1
Glutamate-rich WD repeat-containing protein 1.
   
  
 0.905
WDR75
WD repeat domain 75.
   
 
 0.904
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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