TIFA protein (Macaca mulatta) - STRING interaction network

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

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Score

TIFA

TRAF-interacting protein with FHA domain-containing protein A. (185 aa)

Predicted Functional Partners:

TRAF6

0.947

ALPK1

0.909

TRAF2

0.741

TRAF1

0.620

TRAF4

0.608

TRAF5

0.608

TRAF3

0.607

IRAK1

0.570

TRAFD1

0.554

IKBKG

0.529

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALPK1	TIFA	ENSMMUP00000018497	ENSMMUP00000020450	Alpha kinase 1.	TRAF-interacting protein with FHA domain-containing protein A.	0.909
ALPK1	TRAF6	ENSMMUP00000018497	ENSMMUP00000024012	Alpha kinase 1.	TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]	0.644
IKBKG	IRAK1	ENSMMUP00000040739	ENSMMUP00000024614	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Interleukin 1 receptor associated kinase 1.	0.971
IKBKG	TIFA	ENSMMUP00000040739	ENSMMUP00000020450	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TRAF-interacting protein with FHA domain-containing protein A.	0.529
IKBKG	TRAF1	ENSMMUP00000040739	ENSMMUP00000057367	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor-associated factor.	0.720
IKBKG	TRAF2	ENSMMUP00000040739	ENSMMUP00000015133	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.989
IKBKG	TRAF3	ENSMMUP00000040739	ENSMMUP00000066374	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.741
IKBKG	TRAF4	ENSMMUP00000040739	ENSMMUP00000022296	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor-associated factor.	0.406
IKBKG	TRAF5	ENSMMUP00000040739	ENSMMUP00000038268	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.959
IKBKG	TRAF6	ENSMMUP00000040739	ENSMMUP00000024012	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]	0.998
IRAK1	IKBKG	ENSMMUP00000024614	ENSMMUP00000040739	Interleukin 1 receptor associated kinase 1.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.971
IRAK1	TIFA	ENSMMUP00000024614	ENSMMUP00000020450	Interleukin 1 receptor associated kinase 1.	TRAF-interacting protein with FHA domain-containing protein A.	0.570
IRAK1	TRAF1	ENSMMUP00000024614	ENSMMUP00000057367	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor.	0.583
IRAK1	TRAF2	ENSMMUP00000024614	ENSMMUP00000015133	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.952
IRAK1	TRAF3	ENSMMUP00000024614	ENSMMUP00000066374	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.900
IRAK1	TRAF4	ENSMMUP00000024614	ENSMMUP00000022296	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor.	0.530
IRAK1	TRAF5	ENSMMUP00000024614	ENSMMUP00000038268	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.597
IRAK1	TRAF6	ENSMMUP00000024614	ENSMMUP00000024012	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]	0.999
TIFA	ALPK1	ENSMMUP00000020450	ENSMMUP00000018497	TRAF-interacting protein with FHA domain-containing protein A.	Alpha kinase 1.	0.909
TIFA	IKBKG	ENSMMUP00000020450	ENSMMUP00000040739	TRAF-interacting protein with FHA domain-containing protein A.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.529