Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGF2RInsulin like growth factor 2 receptor. (2491 aa)    
Predicted Functional Partners:
M6PR
Mannose-6-phosphate receptor, cation dependent.
   
 
0.996
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
   
 
 0.984
IGF2
Insulin like growth factor 2.
    
 
 0.967
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 
 0.949
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
    
 
 0.935
PLIN3
Perilipin; Belongs to the perilipin family.
   
 0.877
VPS26A
Vacuolar protein sorting-associated protein 26A isoform 1.
    
 
 0.827
GAK
Cyclin G associated kinase.
   
 
 0.820
IGF1R
Tyrosine-protein kinase receptor.
   
  
 0.779
VTI1A
t-SNARE coiled-coil homology domain-containing protein.
   
 0.752
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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