Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (321 aa)    
Predicted Functional Partners:
STAB2
Stabilin 2.
   
 0.911
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 
 0.881
CCL21
C-C motif chemokine 21; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity).
   
  
 0.811
CD68
CD68 molecule.
      
 0.787
VEGFD
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
 
 0.774
FLT4
Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 
 0.765
PDPN
Podoplanin.
    
 0.745
MRC1
Uncharacterized protein.
   
 0.741
CD34
CD34 molecule.
   
  
 0.740
CCR7
C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.
    
 0.736
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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