NTF4 protein (Macaca mulatta) - STRING interaction network

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NTF4

NGF domain-containing protein; Belongs to the NGF-beta family. (210 aa)

Predicted Functional Partners:

NTRK2

0.998

NTRK1

0.976

BDNF

0.942

NTRK3

0.913

NGFR

0.900

FRS2

0.812

PLCG1

0.775

GDNF

0.754

RET

0.747

NTN5

0.716

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	FRS2	ENSMMUP00000059263	ENSMMUP00000014180	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Fibroblast growth factor receptor substrate 2.	0.851
BDNF	GDNF	ENSMMUP00000059263	ENSMMUP00000024951	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Glial cell derived neurotrophic factor.	0.953
BDNF	NGFR	ENSMMUP00000059263	ENSMMUP00000019165	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Nerve growth factor receptor.	0.904
BDNF	NTF4	ENSMMUP00000059263	ENSMMUP00000020751	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	NGF domain-containing protein; Belongs to the NGF-beta family.	0.942
BDNF	NTRK1	ENSMMUP00000059263	ENSMMUP00000016316	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Tyrosine-protein kinase receptor.	0.967
BDNF	NTRK2	ENSMMUP00000059263	ENSMMUP00000073592	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Tyrosine-protein kinase receptor.	0.998
BDNF	NTRK3	ENSMMUP00000059263	ENSMMUP00000047448	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Tyrosine-protein kinase receptor.	0.920
BDNF	PLCG1	ENSMMUP00000059263	ENSMMUP00000056589	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.664
BDNF	RET	ENSMMUP00000059263	ENSMMUP00000020196	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.762
FRS2	BDNF	ENSMMUP00000014180	ENSMMUP00000059263	Fibroblast growth factor receptor substrate 2.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.851
FRS2	GDNF	ENSMMUP00000014180	ENSMMUP00000024951	Fibroblast growth factor receptor substrate 2.	Glial cell derived neurotrophic factor.	0.423
FRS2	NTF4	ENSMMUP00000014180	ENSMMUP00000020751	Fibroblast growth factor receptor substrate 2.	NGF domain-containing protein; Belongs to the NGF-beta family.	0.812
FRS2	NTRK1	ENSMMUP00000014180	ENSMMUP00000016316	Fibroblast growth factor receptor substrate 2.	Tyrosine-protein kinase receptor.	0.987
FRS2	NTRK2	ENSMMUP00000014180	ENSMMUP00000073592	Fibroblast growth factor receptor substrate 2.	Tyrosine-protein kinase receptor.	0.932
FRS2	NTRK3	ENSMMUP00000014180	ENSMMUP00000047448	Fibroblast growth factor receptor substrate 2.	Tyrosine-protein kinase receptor.	0.712
FRS2	RET	ENSMMUP00000014180	ENSMMUP00000020196	Fibroblast growth factor receptor substrate 2.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.808
GDNF	BDNF	ENSMMUP00000024951	ENSMMUP00000059263	Glial cell derived neurotrophic factor.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.953
GDNF	FRS2	ENSMMUP00000024951	ENSMMUP00000014180	Glial cell derived neurotrophic factor.	Fibroblast growth factor receptor substrate 2.	0.423
GDNF	NGFR	ENSMMUP00000024951	ENSMMUP00000019165	Glial cell derived neurotrophic factor.	Nerve growth factor receptor.	0.650
GDNF	NTF4	ENSMMUP00000024951	ENSMMUP00000020751	Glial cell derived neurotrophic factor.	NGF domain-containing protein; Belongs to the NGF-beta family.	0.754