| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BDNF | EPHA2 | ENSMMUP00000059263 | ENSMMUP00000079185 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | EPH receptor A2. | 0.723 |
| BDNF | IGF1R | ENSMMUP00000059263 | ENSMMUP00000016141 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Tyrosine-protein kinase receptor. | 0.824 |
| BDNF | MET | ENSMMUP00000059263 | ENSMMUP00000008920 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Uncharacterized protein. | 0.722 |
| BDNF | NGF | ENSMMUP00000059263 | ENSMMUP00000046298 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Nerve growth factor; Belongs to the NGF-beta family. | 0.910 |
| BDNF | NGFR | ENSMMUP00000059263 | ENSMMUP00000019165 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Nerve growth factor receptor. | 0.907 |
| BDNF | NTF4 | ENSMMUP00000059263 | ENSMMUP00000020751 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | NGF domain-containing protein; Belongs to the NGF-beta family. | 0.932 |
| BDNF | NTRK1 | ENSMMUP00000059263 | ENSMMUP00000016316 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Tyrosine-protein kinase receptor. | 0.945 |
| BDNF | NTRK2 | ENSMMUP00000059263 | ENSMMUP00000073592 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Tyrosine-protein kinase receptor. | 0.996 |
| BDNF | NTRK3 | ENSMMUP00000059263 | ENSMMUP00000047448 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Tyrosine-protein kinase receptor. | 0.884 |
| BDNF | PDGFRB | ENSMMUP00000059263 | ENSMMUP00000015166 | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. | 0.727 |
| EPHA2 | BDNF | ENSMMUP00000079185 | ENSMMUP00000059263 | EPH receptor A2. | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | 0.723 |
| EPHA2 | NGF | ENSMMUP00000079185 | ENSMMUP00000046298 | EPH receptor A2. | Nerve growth factor; Belongs to the NGF-beta family. | 0.721 |
| EPHA2 | NTF4 | ENSMMUP00000079185 | ENSMMUP00000020751 | EPH receptor A2. | NGF domain-containing protein; Belongs to the NGF-beta family. | 0.705 |
| IGF1R | BDNF | ENSMMUP00000016141 | ENSMMUP00000059263 | Tyrosine-protein kinase receptor. | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | 0.824 |
| IGF1R | NGF | ENSMMUP00000016141 | ENSMMUP00000046298 | Tyrosine-protein kinase receptor. | Nerve growth factor; Belongs to the NGF-beta family. | 0.783 |
| IGF1R | NTF4 | ENSMMUP00000016141 | ENSMMUP00000020751 | Tyrosine-protein kinase receptor. | NGF domain-containing protein; Belongs to the NGF-beta family. | 0.708 |
| MET | BDNF | ENSMMUP00000008920 | ENSMMUP00000059263 | Uncharacterized protein. | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | 0.722 |
| MET | NGF | ENSMMUP00000008920 | ENSMMUP00000046298 | Uncharacterized protein. | Nerve growth factor; Belongs to the NGF-beta family. | 0.726 |
| MET | NTF4 | ENSMMUP00000008920 | ENSMMUP00000020751 | Uncharacterized protein. | NGF domain-containing protein; Belongs to the NGF-beta family. | 0.705 |
| MET | NTRK1 | ENSMMUP00000008920 | ENSMMUP00000016316 | Uncharacterized protein. | Tyrosine-protein kinase receptor. | 0.402 |