CSNK2A2 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CSNK2A2

Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)

Predicted Functional Partners:

CSNK2A1

0.996

CSNK2B

0.981

PCGF5

0.975

PTEN

0.965

PCGF3

0.964

DVL1

0.962

DVL3

0.958

DVL2

0.958

RING1

0.957

RNF2

0.957

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSNK2A1	CSNK2A2	ENSMMUP00000037657	ENSMMUP00000020899	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	0.996
CSNK2A1	CSNK2B	ENSMMUP00000037657	ENSMMUP00000006999	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	Chimera Csnk2b-Ly6g5b splicing isoform 992.	0.984
CSNK2A1	DVL1	ENSMMUP00000037657	ENSMMUP00000046582	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	Dishevelled segment polarity protein 1.	0.971
CSNK2A1	DVL2	ENSMMUP00000037657	ENSMMUP00000061251	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	Dishevelled segment polarity protein 2.	0.966
CSNK2A1	DVL3	ENSMMUP00000037657	ENSMMUP00000008631	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	Segment polarity protein dishevelled homolog DVL-3.	0.971
CSNK2A1	PCGF3	ENSMMUP00000037657	ENSMMUP00000065458	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.850
CSNK2A1	PCGF5	ENSMMUP00000037657	ENSMMUP00000045191	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	Polycomb group ring finger 5.	0.888
CSNK2A1	PTEN	ENSMMUP00000037657	ENSMMUP00000011055	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.971
CSNK2A1	RING1	ENSMMUP00000037657	ENSMMUP00000005154	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase RING1; Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG P [...]	0.808
CSNK2A1	RNF2	ENSMMUP00000037657	ENSMMUP00000018239	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase RING2.	0.829
CSNK2A2	CSNK2A1	ENSMMUP00000020899	ENSMMUP00000037657	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily.	0.996
CSNK2A2	CSNK2B	ENSMMUP00000020899	ENSMMUP00000006999	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Chimera Csnk2b-Ly6g5b splicing isoform 992.	0.981
CSNK2A2	DVL1	ENSMMUP00000020899	ENSMMUP00000046582	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Dishevelled segment polarity protein 1.	0.962
CSNK2A2	DVL2	ENSMMUP00000020899	ENSMMUP00000061251	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Dishevelled segment polarity protein 2.	0.958
CSNK2A2	DVL3	ENSMMUP00000020899	ENSMMUP00000008631	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Segment polarity protein dishevelled homolog DVL-3.	0.958
CSNK2A2	PCGF3	ENSMMUP00000020899	ENSMMUP00000065458	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.964
CSNK2A2	PCGF5	ENSMMUP00000020899	ENSMMUP00000045191	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Polycomb group ring finger 5.	0.975
CSNK2A2	PTEN	ENSMMUP00000020899	ENSMMUP00000011055	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.965
CSNK2A2	RING1	ENSMMUP00000020899	ENSMMUP00000005154	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase RING1; Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG P [...]	0.957
CSNK2A2	RNF2	ENSMMUP00000020899	ENSMMUP00000018239	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase RING2.	0.957