Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (435 aa)    
Predicted Functional Partners:
YAP1
Yes associated protein 1.
   
 0.996
TEAD1
TEA domain transcription factor 1.
  
0.995
TEAD2
TEA domain transcription factor 2.
  
0.995
WWTR1
WW domain containing transcription regulator 1.
   
 0.993
TCF7L2
Transcription factor 7 like 2.
    
 0.886
TCF7
Transcription factor 7.
    
 0.858
LEF1
Lymphoid enhancer binding factor 1.
    
 0.847
TCF7L1
Transcription factor 7 like 1.
    
  0.844
VGLL4
Uncharacterized protein.
    
 
 0.820
VGLL1
Vestigial like family member 1.
    
 
 0.777
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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