Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARL6IP4ADP ribosylation factor like GTPase 6 interacting protein 4. (406 aa)    
Predicted Functional Partners:
ENSA
Endosulfine alpha; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.
      
 0.768
DGKI
Diacylglycerol kinase.
      
 0.766
PIP4K2B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.
    
   0.746
PIP4K2C
Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma isoform a.
    
   0.739
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
    
   0.727
EIF3J
Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
    
   0.724
GPALPP1
GPALPP motifs containing 1.
    
   0.708
ZRANB2
Zinc finger Ran-binding domain-containing protein 2; May interfere with constitutive 5'-splice site selection. Belongs to the ZRANB2 family.
    
 
 0.703
ENSMMUP00000044327
annotation not available
    
 
 0.703
C2CD3
C2 domain containing 3 centriole elongation regulator.
    
   0.666
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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