Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CENPACentromere protein A. (138 aa)    
Predicted Functional Partners:
HJURP
Holliday junction recognition protein.
   
 0.997
AURKB
Aurora kinase B; Belongs to the protein kinase superfamily.
   
 
 0.989
CCNA2
Cyclin-A2; Belongs to the cyclin family.
   
 0.989
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.979
PLK1
Serine/threonine-protein kinase PLK.
   
 0.978
CENPT
Centromere protein T.
   
 0.977
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.974
CENPE
Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.971
KIF2C
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.970
CENPB
Centromere protein B.
    
 
 0.966
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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