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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106994494TFIIS N-terminal domain-containing protein. (529 aa)    
Predicted Functional Partners:
LEO1
RNA polymerase-associated protein LEO1.
    
 0.973
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.955
WDR61
WD repeat domain 61.
    
 0.815
CTR9
CTR9 homolog, Paf1/RNA polymerase II complex component.
    
 0.807
F6XRN0_MACMU
Ubiquitin-like domain-containing protein.
    
 0.804
ELOB
Transcription elongation factor B polypeptide 2 isoform a.
    
 0.804
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 0.777
CDC73
Parafibromin.
    
 0.758
CDK9
Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily.
     
 0.737
SUPT5H
Transcription elongation factor SPT5.
   
 0.709
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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