STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLG1Disks large homolog 1 isoform 2; Belongs to the MAGUK family. (926 aa)    
Predicted Functional Partners:
PTEN
Uncharacterized protein.
   
 0.963
LLGL1
LLGL scribble cell polarity complex component 1.
   
 0.949
LLGL2
LLGL scribble cell polarity complex component 2.
   
 0.942
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.930
ZAP70
Tyrosine-protein kinase.
    
 0.928
DLG2
Discs large MAGUK scaffold protein 2.
  
  
0.928
MAPK14
Mitogen-activated protein kinase.
   
 0.909
MAPK11
Mitogen-activated protein kinase.
    
 0.909
GRIA1
Uncharacterized protein.
   
 0.876
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
    
 0.854
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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