STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD101CD101 molecule. (1021 aa)    
Predicted Functional Partners:
IL2RA
Interleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
  
 
 0.791
AVPR1B
Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
    
 0.755
IL31
Uncharacterized protein.
      
 0.709
EIF2S2
eIF2B_5 domain-containing protein.
   
  
 0.669
WNT8A
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 
 0.506
TET2
Tet methylcytosine dioxygenase 2.
      
 0.446
FCGR3
Low affinity immunoglobulin gamma Fc region receptor III; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Binds IgG1 and IgG2 (By similarity).
    
 0.434
AKAP5
A-kinase anchoring protein 5.
     
 0.426
ITGAE
Integrin subunit alpha E; Belongs to the integrin alpha chain family.
    
 0.401
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.