STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK1Serine/threonine-protein kinase PLK. (603 aa)    
Predicted Functional Partners:
CCNB1
G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.
   
 0.997
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
0.996
CDC20
Cell division cycle protein 20 homolog.
   
 0.996
CDC25C
Cell division cycle 25C.
   
 0.994
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 0.989
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.986
PKMYT1
Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily.
   
0.981
CDC25A
M-phase inducer phosphatase 1 isoform a.
   
 0.977
CDC25B
Cell division cycle 25B.
   
 0.977
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.976
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.