STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KSR1Kinase suppressor of ras 1. (762 aa)    
Predicted Functional Partners:
RAF1
Uncharacterized protein.
    
0.982
BRAP
BRCA1-associated protein.
   
 0.964
MAP2K1
Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
 0.946
KSR2
Kinase suppressor of ras 2.
     
0.932
LSP1
Lymphocyte specific protein 1.
    
 0.928
MAP2K2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.865
PLK3
Serine/threonine-protein kinase PLK.
    
0.853
MAP2K5
Dual specificity mitogen-activated protein kinase kinase 5 isoform A; Belongs to the protein kinase superfamily.
   
 0.777
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
0.759
MRAS
Uncharacterized protein.
   
 0.753
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.