STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEFVMEFV innate immuity regulator, pyrin. (786 aa)    
Predicted Functional Partners:
CASP1
Caspase 1; Belongs to the peptidase C14A family.
   
 0.996
PYCARD
Apoptosis-associated speck-like protein containing a CARD isoform a.
    
 0.995
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 0.987
PKN2
Protein kinase N2.
    
 0.961
AIM2
Absent in melanoma 2.
   
 0.958
NLRP1
Uncharacterized protein.
   
 0.948
PKN1
Protein kinase N1.
   
 0.944
NLRC4
NLR family CARD domain containing 4.
    
 
 0.907
YWHAE
14-3-3 protein epsilon; Belongs to the 14-3-3 family.
    
 0.906
RPS6KA1
Ribosomal protein S6 kinase.
   
 
  0.903
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.