MEF2A protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HDAC4	HDAC5	ENSMMUP00000007984	ENSMMUP00000061782	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.961
HDAC4	MEF2A	ENSMMUP00000007984	ENSMMUP00000054321	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte-specific enhancer factor 2A isoform 2.	0.857
HDAC4	MEF2B	ENSMMUP00000007984	ENSMMUP00000048696	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	MADS-box domain-containing protein.	0.443
HDAC4	MEF2C	ENSMMUP00000007984	ENSMMUP00000042872	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte-specific enhancer factor 2C isoform 1.	0.952
HDAC4	MEF2D	ENSMMUP00000007984	ENSMMUP00000021952	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte-specific enhancer factor 2D.	0.854
HDAC4	MYOD1	ENSMMUP00000007984	ENSMMUP00000008443	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.435
HDAC5	HDAC4	ENSMMUP00000061782	ENSMMUP00000007984	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.961
HDAC5	MEF2A	ENSMMUP00000061782	ENSMMUP00000054321	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte-specific enhancer factor 2A isoform 2.	0.855
HDAC5	MEF2B	ENSMMUP00000061782	ENSMMUP00000048696	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	MADS-box domain-containing protein.	0.519
HDAC5	MEF2C	ENSMMUP00000061782	ENSMMUP00000042872	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte-specific enhancer factor 2C isoform 1.	0.812
HDAC5	MEF2D	ENSMMUP00000061782	ENSMMUP00000021952	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myocyte-specific enhancer factor 2D.	0.830
MEF2A	HDAC4	ENSMMUP00000054321	ENSMMUP00000007984	Myocyte-specific enhancer factor 2A isoform 2.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.857
MEF2A	HDAC5	ENSMMUP00000054321	ENSMMUP00000061782	Myocyte-specific enhancer factor 2A isoform 2.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.855
MEF2A	MEF2B	ENSMMUP00000054321	ENSMMUP00000048696	Myocyte-specific enhancer factor 2A isoform 2.	MADS-box domain-containing protein.	0.855
MEF2A	MEF2C	ENSMMUP00000054321	ENSMMUP00000042872	Myocyte-specific enhancer factor 2A isoform 2.	Myocyte-specific enhancer factor 2C isoform 1.	0.996
MEF2A	MEF2D	ENSMMUP00000054321	ENSMMUP00000021952	Myocyte-specific enhancer factor 2A isoform 2.	Myocyte-specific enhancer factor 2D.	0.995
MEF2A	MYOD1	ENSMMUP00000054321	ENSMMUP00000008443	Myocyte-specific enhancer factor 2A isoform 2.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.912
MEF2A	NFATC1	ENSMMUP00000054321	ENSMMUP00000080336	Myocyte-specific enhancer factor 2A isoform 2.	Nuclear factor of activated T cells 1.	0.915
MEF2A	NFATC2	ENSMMUP00000054321	ENSMMUP00000049038	Myocyte-specific enhancer factor 2A isoform 2.	Nuclear factor of activated T cells 2.	0.929
MEF2A	NFATC3	ENSMMUP00000054321	ENSMMUP00000028763	Myocyte-specific enhancer factor 2A isoform 2.	Nuclear factor of activated T cells 3.	0.912