STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLCNKBChloride channel protein. (826 aa)    
Predicted Functional Partners:
BSND
Barttin CLCNK type accessory beta subunit.
   
 
 0.885
KCNJ1
Potassium voltage-gated channel subfamily J member 1.
   
  
 0.785
CDH16
Cadherin 16.
   
  
 0.677
SLC34A1
Solute carrier family 34 member 1.
   
  
 0.675
AQP2
Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.654
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
      
 0.651
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
      
 0.651
OSTM1
Osteoclastogenesis associated transmembrane protein 1.
   
 0.645
SLC12A3
Solute carrier family 12 member 3.
   
  
 0.644
SLC13A3
Solute carrier family 13 member 3.
  
  
 0.627
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.