STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1883 aa)    
Predicted Functional Partners:
ELMO1
Engulfment and cell motility protein 1 isoform 1.
    
 0.998
CRK
CRK proto-oncogene, adaptor protein.
    
 0.991
ELMO2
Engulfment and cell motility 2.
    
 0.990
RHOG
Rho-related GTP-binding protein RhoG.
   
 0.987
ELMO3
Engulfment and cell motility 3.
    
 0.986
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.975
RAC2
Ras-related C3 botulinum toxin substrate 2.
   
 0.973
RAC3
Ras-related C3 botulinum toxin substrate 3.
   
 0.963
RAC1
Uncharacterized protein.
   
 0.963
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.953
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.