Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KCNA2Potassium voltage-gated channel subfamily A member 2 isoform a; Belongs to the potassium channel family. (499 aa)    
Predicted Functional Partners:
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
   
 0.890
KCNAB1
Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.
   
 0.775
KCNA5
Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family.
   
 0.748
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
  0.742
MZF1
Uncharacterized protein.
      
 0.660
CACNA1B
Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.
   
 
 0.641
KCNAB3
Trafficking protein particle complex 1.
   
 0.631
KCNA3
Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family.
   
 0.608
KCNA4
Voltage-gated potassium channel subunit Kv1.4; Belongs to the potassium channel family.
   
 0.608
UBA52
Ubiquitin-60S ribosomal protein L40.
   
 0.606
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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