STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYEF2Myelin expression factor 2. (600 aa)    
Predicted Functional Partners:
XAB2
Pre-mRNA-splicing factor SYF1.
   
 0.696
CRNKL1
Crooked neck pre-mRNA splicing factor 1.
    
 0.681
ISY1
Uncharacterized protein.
   
 0.679
SYF2
SYF2 pre-mRNA splicing factor.
    
 0.678
HNRNPM
Heterogeneous nuclear ribonucleoprotein M.
  
0.671
TFIP11
Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...]
    
 0.652
CWF19L2
CWF19 like cell cycle control factor 2.
    
  0.625
LUC7L3
LUC7 like 3 pre-mRNA splicing factor.
    
 
 0.624
CCDC12
Coiled-coil domain containing 12.
    
 0.623
STXBP6
Syntaxin-binding protein 6.
    
 
 0.617
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.