node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AANAT | ASMT | ENSMMUP00000024958 | ENSMMUP00000080948 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. | 0.995 |
AANAT | DDC | ENSMMUP00000024958 | ENSMMUP00000026285 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Aromatic-L-amino-acid decarboxylase. | 0.945 |
AANAT | ESCO2 | ENSMMUP00000024958 | ENSMMUP00000021066 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Establishment of sister chromatid cohesion N-acetyltransferase 2. | 0.732 |
AANAT | IDO1 | ENSMMUP00000024958 | ENSMMUP00000032133 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Indoleamine 2,3-dioxygenase 1. | 0.913 |
AANAT | IDO2 | ENSMMUP00000024958 | ENSMMUP00000025362 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Indoleamine 2,3-dioxygenase 2. | 0.929 |
AANAT | INMT | ENSMMUP00000024958 | ENSMMUP00000067770 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Uncharacterized protein. | 0.901 |
AANAT | MAOA | ENSMMUP00000024958 | ENSMMUP00000025612 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Amine oxidase. | 0.933 |
AANAT | MAOB | ENSMMUP00000024958 | ENSMMUP00000069352 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Amine oxidase. | 0.933 |
AANAT | MTNR1B | ENSMMUP00000024958 | ENSMMUP00000062349 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Uncharacterized protein. | 0.741 |
AANAT | TPH1 | ENSMMUP00000024958 | ENSMMUP00000008013 | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | Tryptophan hydroxylase 1. | 0.757 |
ASMT | AANAT | ENSMMUP00000080948 | ENSMMUP00000024958 | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | 0.995 |
ASMT | DDC | ENSMMUP00000080948 | ENSMMUP00000026285 | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. | Aromatic-L-amino-acid decarboxylase. | 0.497 |
ASMT | ESCO2 | ENSMMUP00000080948 | ENSMMUP00000021066 | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. | Establishment of sister chromatid cohesion N-acetyltransferase 2. | 0.431 |
ASMT | IDO1 | ENSMMUP00000080948 | ENSMMUP00000032133 | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. | Indoleamine 2,3-dioxygenase 1. | 0.915 |
ASMT | IDO2 | ENSMMUP00000080948 | ENSMMUP00000025362 | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. | Indoleamine 2,3-dioxygenase 2. | 0.915 |
ASMT | MTNR1B | ENSMMUP00000080948 | ENSMMUP00000062349 | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. | Uncharacterized protein. | 0.574 |
ASMT | TPH1 | ENSMMUP00000080948 | ENSMMUP00000008013 | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. | Tryptophan hydroxylase 1. | 0.772 |
DDC | AANAT | ENSMMUP00000026285 | ENSMMUP00000024958 | Aromatic-L-amino-acid decarboxylase. | Serotonin N-acetyltransferase; Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N- acetylserotonin, the penultimate step in the synthesis of melatonin. Belongs to the acetyltransferase family. AANAT subfamily. | 0.945 |
DDC | ASMT | ENSMMUP00000026285 | ENSMMUP00000080948 | Aromatic-L-amino-acid decarboxylase. | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. | 0.497 |
DDC | IDO1 | ENSMMUP00000026285 | ENSMMUP00000032133 | Aromatic-L-amino-acid decarboxylase. | Indoleamine 2,3-dioxygenase 1. | 0.908 |