STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GBP3Guanylate binding protein 3. (595 aa)    
Predicted Functional Partners:
GBP7
Guanylate binding protein 7.
  
0.939
IFIT3
Interferon induced protein with tetratricopeptide repeats 3.
   
  
 0.677
STAT1
Signal transducer and activator of transcription.
   
 
 0.639
PDLIM5
PDZ and LIM domain 5.
      
 0.634
RNF6
Ring finger protein 6.
   
 
 0.605
ISG20
Exonuclease domain-containing protein.
   
  
 0.558
CLEC7A
C-type lectin domain family 7 member A; Lectin that functions as pattern receptor specific for beta- 1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Induces phosphorylation of SCIMP after binding beta-glucans (By similarity). Necessary for the TLR2- mediated inflammatory response and for TLR2-mediated activation of NF- kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does [...]
   
  
 0.534
IFIT2
Interferon-induced protein with tetratricopeptide repeats 2.
   
  
 0.524
IRF1
Interferon regulatory factor.
   
 
 0.516
ISG15
Ubiquitin-like protein ISG15.
   
  
 0.509
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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