STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CGASCyclic GMP-AMP synthase. (573 aa)    
Predicted Functional Partners:
MNDA
Gamma-interferon-inducible protein 16 isoform 2.
    
 
 0.886
IRF3
Interferon regulatory factor 3.
      
 0.864
TBK1
Serine/threonine-protein kinase TBK1.
   
  
 0.845
DDX41
DEAD-box helicase 41.
      
 0.822
STING1
Stimulator of interferon protein.
    
 0.798
MAVS
Mitochondrial antiviral-signaling protein isoform 1.
      
 0.796
AIM2
Absent in melanoma 2.
   
 
 0.789
IRF7
Interferon regulatory factor 7.
   
  
 0.750
H2AC20
Histone H2A; Belongs to the histone H2A family.
    
 
 0.745
NONO
Uncharacterized protein.
      
 0.742
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.