STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRAT2FRAT regulator of WNT signaling pathway 2. (233 aa)    
Predicted Functional Partners:
GSK3B
Glycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily.
    
 0.986
DVL1
Dishevelled segment polarity protein 1.
    
 0.932
FRAT1
FRAT regulator of WNT signaling pathway 1.
  
 
 
0.921
DVL3
Segment polarity protein dishevelled homolog DVL-3.
    
 0.912
DVL2
Dishevelled segment polarity protein 2.
    
 0.912
OGFRL1
Opioid growth factor receptor like 1.
    
 0.778
MACF1
Microtubule actin crosslinking factor 1.
      
 0.598
TP53BP1
Tumor protein p53 binding protein 1.
      
 0.583
AXIN1
Axin 1.
    
 0.536
ELK3
ETS domain-containing protein Elk-3.
      
 0.472
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.