STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR89AGolgi pH regulator B. (455 aa)    
Predicted Functional Partners:
OSBPL8
Oxysterol-binding protein; Belongs to the OSBP family.
 
      0.852
POLR3GL
DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
   
  
 0.849
TTYH1
Protein tweety homolog; Probable chloride channel.
      
 0.785
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
   
  
 0.751
SLC35D1
Solute carrier family 35 member D1.
   
  
 0.699
MYSM1
Myb like, SWIRM and MPN domains 1.
      
 0.683
GTPBP8
GTP binding protein 8 (putative).
   
  
 0.662
AQP6
Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family.
      
 0.647
ATP6V0A2
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
      
 0.506
RER1
Retention in endoplasmic reticulum sorting receptor 1.
   
  
 0.506
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.