STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPHS1NPHS1 adhesion molecule, nephrin. (1221 aa)    
Predicted Functional Partners:
KIRREL1
Kirre like nephrin family adhesion molecule 1.
   
0.953
KIRREL3
Kirre like nephrin family adhesion molecule 3.
   
0.942
KIRREL2
Kirre like nephrin family adhesion molecule 2.
   
0.920
NPHS2
NPHS2 stomatin family member, podocin.
    
 0.871
CD2AP
CD2-associated protein.
    
 0.857
NCK1
Cytoplasmic protein.
    
 0.827
NCK2
Cytoplasmic protein.
    
 0.764
WASL
Neural Wiskott-Aldrich syndrome protein.
     
 0.752
PODXL
Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.
    
 0.735
WT1
WT1 transcription factor.
      
 0.728
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.