STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MS4A4AUncharacterized protein. (220 aa)    
Predicted Functional Partners:
VSIG4
V-set and immunoglobulin domain containing 4.
   
  
 0.625
ABCA7
ATP binding cassette subfamily A member 7.
      
 0.573
CD163
CD163 molecule.
   
 0.562
CD33
CD33 molecule.
   
 0.559
MS4A6E
Membrane spanning 4-domains A6E.
  
  
0.550
NME8
NME/NM23 family member 8.
      
 0.540
ZCWPW1
Zinc finger CW-type and PWWP domain containing 1.
      
 0.540
CASS4
Cas scaffold protein family member 4.
      
 0.534
MS4A6A
Membrane spanning 4-domains A6A.
  
  
0.513
TYROBP
TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]
   
  
 0.497
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.