PSPC1 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC22	NONO	ENSMMUP00000065197	ENSMMUP00000040988	Uncharacterized protein.	Uncharacterized protein.	0.504
CCDC22	PSPC1	ENSMMUP00000065197	ENSMMUP00000036495	Uncharacterized protein.	Paraspeckle component 1.	0.662
FUS	HNRNPK	ENSMMUP00000025800	ENSMMUP00000080326	Tripartite motif containing 72.	Heterogeneous nuclear ribonucleoprotein K isoform a.	0.811
FUS	NONO	ENSMMUP00000025800	ENSMMUP00000040988	Tripartite motif containing 72.	Uncharacterized protein.	0.771
FUS	NUDT21	ENSMMUP00000025800	ENSMMUP00000055474	Tripartite motif containing 72.	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.411
FUS	PSPC1	ENSMMUP00000025800	ENSMMUP00000036495	Tripartite motif containing 72.	Paraspeckle component 1.	0.589
FUS	PTBP1	ENSMMUP00000025800	ENSMMUP00000042296	Tripartite motif containing 72.	Polypyrimidine tract binding protein 1.	0.551
FUS	RBM14	ENSMMUP00000025800	ENSMMUP00000010284	Tripartite motif containing 72.	RNA-binding protein 14 isoform 1.	0.511
FUS	SFPQ	ENSMMUP00000025800	ENSMMUP00000025177	Tripartite motif containing 72.	Splicing factor, proline-and glutamine-rich.	0.896
FUS	U2AF2	ENSMMUP00000025800	ENSMMUP00000006397	Tripartite motif containing 72.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.720
HNRNPK	FUS	ENSMMUP00000080326	ENSMMUP00000025800	Heterogeneous nuclear ribonucleoprotein K isoform a.	Tripartite motif containing 72.	0.811
HNRNPK	NONO	ENSMMUP00000080326	ENSMMUP00000040988	Heterogeneous nuclear ribonucleoprotein K isoform a.	Uncharacterized protein.	0.623
HNRNPK	NUDT21	ENSMMUP00000080326	ENSMMUP00000055474	Heterogeneous nuclear ribonucleoprotein K isoform a.	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.677
HNRNPK	PSPC1	ENSMMUP00000080326	ENSMMUP00000036495	Heterogeneous nuclear ribonucleoprotein K isoform a.	Paraspeckle component 1.	0.631
HNRNPK	PTBP1	ENSMMUP00000080326	ENSMMUP00000042296	Heterogeneous nuclear ribonucleoprotein K isoform a.	Polypyrimidine tract binding protein 1.	0.967
HNRNPK	RBM14	ENSMMUP00000080326	ENSMMUP00000010284	Heterogeneous nuclear ribonucleoprotein K isoform a.	RNA-binding protein 14 isoform 1.	0.678
HNRNPK	SFPQ	ENSMMUP00000080326	ENSMMUP00000025177	Heterogeneous nuclear ribonucleoprotein K isoform a.	Splicing factor, proline-and glutamine-rich.	0.746
HNRNPK	U2AF2	ENSMMUP00000080326	ENSMMUP00000006397	Heterogeneous nuclear ribonucleoprotein K isoform a.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.891
NONO	CCDC22	ENSMMUP00000040988	ENSMMUP00000065197	Uncharacterized protein.	Uncharacterized protein.	0.504
NONO	FUS	ENSMMUP00000040988	ENSMMUP00000025800	Uncharacterized protein.	Tripartite motif containing 72.	0.771