STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF4Rap guanine nucleotide exchange factor 4. (1047 aa)    
Predicted Functional Partners:
RAP1B
Ras-related protein Rap-1b isoform 1.
    
 0.993
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.988
PCLO
Piccolo presynaptic cytomatrix protein.
   
 0.951
RAPGEF3
Rap guanine nucleotide exchange factor 3.
  
  
 
0.949
RRAS
Ras-related protein R-Ras.
    
 0.948
RRAS2
Ras-related protein R-Ras2 isoform a.
    
 0.948
ADCY8
Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 
 0.941
ADCY6
Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 
 0.941
ADCY5
Adenylate cyclase 5.
   
 
 0.930
ADCY7
Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 
 0.930
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (54%) [HD]