STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (826 aa)    
Predicted Functional Partners:
VHL
Von Hippel-Lindau disease tumor suppressor isoform 1.
    
 0.999
EP300
Histone acetyltransferase p300.
   
 0.999
ARNT
Uncharacterized protein.
   
0.998
EGLN1
Uncharacterized protein.
   
 0.998
CREBBP
CREB-binding protein isoform a.
   
 0.997
EGLN3
Egl nine homolog 3.
    
 0.993
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2.
   
0.993
CUL2
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.990
ELOB
Transcription elongation factor B polypeptide 2 isoform a.
    
 0.988
EPAS1
Endothelial PAS domain protein 1.
   
0.986
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.