DHX57 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DHX57

DExH-box helicase 57. (1387 aa)

Predicted Functional Partners:

ITSN2

0.943

STXBP4

0.863

MLST8

0.814

NHLRC1

0.795

KIF13A

0.781

ITSN1

0.752

AP2M1

0.692

TRIM59

0.659

AP2S1

0.658

PDCD11

0.635

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2M1	AP2S1	ENSMMUP00000045495	ENSMMUP00000046196	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Clat_adaptor_s domain-containing protein.	0.997
AP2M1	DHX57	ENSMMUP00000045495	ENSMMUP00000027725	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	DExH-box helicase 57.	0.692
AP2M1	ITSN1	ENSMMUP00000045495	ENSMMUP00000042520	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Intersectin 1.	0.985
AP2M1	ITSN2	ENSMMUP00000045495	ENSMMUP00000012316	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Intersectin 2.	0.997
AP2S1	AP2M1	ENSMMUP00000046196	ENSMMUP00000045495	Clat_adaptor_s domain-containing protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.997
AP2S1	DHX57	ENSMMUP00000046196	ENSMMUP00000027725	Clat_adaptor_s domain-containing protein.	DExH-box helicase 57.	0.658
AP2S1	ITSN1	ENSMMUP00000046196	ENSMMUP00000042520	Clat_adaptor_s domain-containing protein.	Intersectin 1.	0.984
AP2S1	ITSN2	ENSMMUP00000046196	ENSMMUP00000012316	Clat_adaptor_s domain-containing protein.	Intersectin 2.	0.997
DHX57	AP2M1	ENSMMUP00000027725	ENSMMUP00000045495	DExH-box helicase 57.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.692
DHX57	AP2S1	ENSMMUP00000027725	ENSMMUP00000046196	DExH-box helicase 57.	Clat_adaptor_s domain-containing protein.	0.658
DHX57	ITSN1	ENSMMUP00000027725	ENSMMUP00000042520	DExH-box helicase 57.	Intersectin 1.	0.752
DHX57	ITSN2	ENSMMUP00000027725	ENSMMUP00000012316	DExH-box helicase 57.	Intersectin 2.	0.943
DHX57	KIF13A	ENSMMUP00000027725	ENSMMUP00000031029	DExH-box helicase 57.	Kinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.781
DHX57	MLST8	ENSMMUP00000027725	ENSMMUP00000025274	DExH-box helicase 57.	MTOR associated protein, LST8 homolog.	0.814
DHX57	NHLRC1	ENSMMUP00000027725	ENSMMUP00000021863	DExH-box helicase 57.	NHL repeat containing E3 ubiquitin protein ligase 1.	0.795
DHX57	PDCD11	ENSMMUP00000027725	ENSMMUP00000009253	DExH-box helicase 57.	Programmed cell death 11.	0.635
DHX57	STXBP4	ENSMMUP00000027725	ENSMMUP00000055856	DExH-box helicase 57.	Syntaxin-binding protein 4.	0.863
DHX57	TRIM59	ENSMMUP00000027725	ENSMMUP00000073049	DExH-box helicase 57.	Tripartite motif-containing protein 59.	0.659
ITSN1	AP2M1	ENSMMUP00000042520	ENSMMUP00000045495	Intersectin 1.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.985
ITSN1	AP2S1	ENSMMUP00000042520	ENSMMUP00000046196	Intersectin 1.	Clat_adaptor_s domain-containing protein.	0.984