Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RGS10RGS domain-containing protein. (196 aa)    
Predicted Functional Partners:
ARHGAP28
Rho GTPase activating protein 28.
   
  
 0.678
TSPAN18
Tetraspanin.
      
 0.672
GNAI3
Guanine nucleotide-binding protein G(K) subunit alpha.
   
 0.666
GNAI1
G protein subunit alpha i1.
   
 0.666
GNAI2
Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1.
   
 0.650
GNAQ
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.624
GNAO1
Guanine nucleotide-binding protein G(O) subunit alpha isoform a.
   
 0.616
GNB5
G protein subunit beta 5.
   
 0.586
NPSR1
Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases.
   
 0.562
GNAT2
G protein subunit alpha transducin 2.
   
 0.548
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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