STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HRASTransforming protein p21. (189 aa)    
Predicted Functional Partners:
RAF1
Uncharacterized protein.
   
 0.998
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.998
RASA1
RAS p21 protein activator 1.
   
 0.995
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.992
RASSF5
Ras association domain family member 5.
    
 0.988
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family.
   
 0.987
AFDN
Afadin, adherens junction formation factor.
    
 0.984
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.982
NF1
Neurofibromin 1.
   
 0.979
RASGRP4
RAS guanyl releasing protein 4.
    
 0.979
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.