PARP3 protein (Macaca mulatta) - STRING interaction network

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Predicted Interactions

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Score

PARP3

Poly [ADP-ribose] polymerase. (532 aa)

Predicted Functional Partners:

PARG

0.945

CASP9

0.920

CASP3

0.920

APLF

0.912

GZMB

0.903

TNKS2

0.823

BRCA2

0.768

FEN1

0.758

LIG3

0.700

C5H4orf27

0.694

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLF	LIG3	ENSMMUP00000045046	ENSMMUP00000006377	Aprataxin and PNKP like factor.	DNA ligase.	0.729
APLF	PARG	ENSMMUP00000045046	ENSMMUP00000078542	Aprataxin and PNKP like factor.	Poly(ADP-ribose) glycohydrolase.	0.715
APLF	PARP3	ENSMMUP00000045046	ENSMMUP00000029228	Aprataxin and PNKP like factor.	Poly [ADP-ribose] polymerase.	0.912
BRCA2	FEN1	ENSMMUP00000009432	ENSMMUP00000008754	BRCA2 DNA repair associated.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.718
BRCA2	LIG3	ENSMMUP00000009432	ENSMMUP00000006377	BRCA2 DNA repair associated.	DNA ligase.	0.410
BRCA2	PARP3	ENSMMUP00000009432	ENSMMUP00000029228	BRCA2 DNA repair associated.	Poly [ADP-ribose] polymerase.	0.768
C5H4orf27	PARG	ENSMMUP00000013398	ENSMMUP00000078542	UPF0609 protein C4orf27.	Poly(ADP-ribose) glycohydrolase.	0.504
C5H4orf27	PARP3	ENSMMUP00000013398	ENSMMUP00000029228	UPF0609 protein C4orf27.	Poly [ADP-ribose] polymerase.	0.694
CASP3	CASP9	ENSMMUP00000070295	ENSMMUP00000023884	Caspase 3; Belongs to the peptidase C14A family.	Caspase-9 isoform alpha preproprotein; Belongs to the peptidase C14A family.	0.989
CASP3	GZMB	ENSMMUP00000070295	ENSMMUP00000018888	Caspase 3; Belongs to the peptidase C14A family.	Granzyme B; Belongs to the peptidase S1 family.	0.958
CASP3	PARP3	ENSMMUP00000070295	ENSMMUP00000029228	Caspase 3; Belongs to the peptidase C14A family.	Poly [ADP-ribose] polymerase.	0.920
CASP9	CASP3	ENSMMUP00000023884	ENSMMUP00000070295	Caspase-9 isoform alpha preproprotein; Belongs to the peptidase C14A family.	Caspase 3; Belongs to the peptidase C14A family.	0.989
CASP9	PARP3	ENSMMUP00000023884	ENSMMUP00000029228	Caspase-9 isoform alpha preproprotein; Belongs to the peptidase C14A family.	Poly [ADP-ribose] polymerase.	0.920
FEN1	BRCA2	ENSMMUP00000008754	ENSMMUP00000009432	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	BRCA2 DNA repair associated.	0.718
FEN1	LIG3	ENSMMUP00000008754	ENSMMUP00000006377	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA ligase.	0.922
FEN1	PARG	ENSMMUP00000008754	ENSMMUP00000078542	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Poly(ADP-ribose) glycohydrolase.	0.657
FEN1	PARP3	ENSMMUP00000008754	ENSMMUP00000029228	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Poly [ADP-ribose] polymerase.	0.758
GZMB	CASP3	ENSMMUP00000018888	ENSMMUP00000070295	Granzyme B; Belongs to the peptidase S1 family.	Caspase 3; Belongs to the peptidase C14A family.	0.958
GZMB	PARP3	ENSMMUP00000018888	ENSMMUP00000029228	Granzyme B; Belongs to the peptidase S1 family.	Poly [ADP-ribose] polymerase.	0.903
LIG3	APLF	ENSMMUP00000006377	ENSMMUP00000045046	DNA ligase.	Aprataxin and PNKP like factor.	0.729