Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KCNAB3Trafficking protein particle complex 1. (569 aa)    
Predicted Functional Partners:
KCNH3
Potassium voltage-gated channel subfamily H member 3.
    
 0.938
OPCML
Opioid binding protein/cell adhesion molecule like.
   
 
 0.833
CACNB1
Calcium voltage-gated channel auxiliary subunit beta 1.
   
  
 0.818
GABRA5
Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.781
KCNA5
Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family.
   
 0.764
NTRK2
Tyrosine-protein kinase receptor.
    
 0.733
KCNA7
Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family.
   
 0.733
KCNC4
Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family.
   
 0.731
SCN1A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 
 0.728
KCNB2
Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family.
   
 0.722
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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