STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (224 aa)    
Predicted Functional Partners:
UBE2V1
TMEM189_B_dmain domain-containing protein.
   
 0.978
RAD18
RAD18 E3 ubiquitin protein ligase.
   
 0.959
RNF20
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 0.920
RNF40
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 0.919
LEO1
RNA polymerase-associated protein LEO1.
   
 0.878
UBA1
Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
  
 0.864
UBA52
Ubiquitin-60S ribosomal protein L40.
   
 0.833
UBE2V2
Ubiquitin-conjugating enzyme E2 variant 2.
   
 0.825
UBC
Uncharacterized protein.
   
 0.823
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.822
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.