SHPK protein (Macaca mulatta) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SHPK

FGGY_N domain-containing protein. (478 aa)

Predicted Functional Partners:

FRYL

0.821

GPD2

0.771

PSMD6

0.749

PSMD4

0.732

PSMD12

0.730

PSMD11

0.728

PSMD2

0.727

PSMD13

0.724

PSMD1

0.708

PSMB4

0.688

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FRYL	SHPK	ENSMMUP00000008821	ENSMMUP00000030791	FRY like transcription coactivator.	FGGY_N domain-containing protein.	0.821
GPD2	SHPK	ENSMMUP00000060392	ENSMMUP00000030791	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.	FGGY_N domain-containing protein.	0.771
PSMB4	PSMD1	ENSMMUP00000027532	ENSMMUP00000015459	Proteasome subunit beta; Belongs to the peptidase T1B family.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.992
PSMB4	PSMD11	ENSMMUP00000027532	ENSMMUP00000073478	Proteasome subunit beta; Belongs to the peptidase T1B family.	Proteasome 26S subunit, non-ATPase 11.	0.997
PSMB4	PSMD12	ENSMMUP00000027532	ENSMMUP00000002837	Proteasome subunit beta; Belongs to the peptidase T1B family.	Proteasome 26S subunit, non-ATPase 12.	0.998
PSMB4	PSMD13	ENSMMUP00000027532	ENSMMUP00000015107	Proteasome subunit beta; Belongs to the peptidase T1B family.	Proteasome 26S subunit, non-ATPase 13.	0.994
PSMB4	PSMD2	ENSMMUP00000027532	ENSMMUP00000001091	Proteasome subunit beta; Belongs to the peptidase T1B family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.993
PSMB4	PSMD4	ENSMMUP00000027532	ENSMMUP00000010469	Proteasome subunit beta; Belongs to the peptidase T1B family.	VWFA domain-containing protein.	0.998
PSMB4	PSMD6	ENSMMUP00000027532	ENSMMUP00000039564	Proteasome subunit beta; Belongs to the peptidase T1B family.	Proteasome 26S subunit, non-ATPase 6.	0.998
PSMB4	SHPK	ENSMMUP00000027532	ENSMMUP00000030791	Proteasome subunit beta; Belongs to the peptidase T1B family.	FGGY_N domain-containing protein.	0.688
PSMD1	PSMB4	ENSMMUP00000015459	ENSMMUP00000027532	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.992
PSMD1	PSMD11	ENSMMUP00000015459	ENSMMUP00000073478	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 11.	0.999
PSMD1	PSMD12	ENSMMUP00000015459	ENSMMUP00000002837	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 12.	0.999
PSMD1	PSMD13	ENSMMUP00000015459	ENSMMUP00000015107	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 13.	0.997
PSMD1	PSMD2	ENSMMUP00000015459	ENSMMUP00000001091	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999
PSMD1	PSMD4	ENSMMUP00000015459	ENSMMUP00000010469	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	VWFA domain-containing protein.	0.997
PSMD1	PSMD6	ENSMMUP00000015459	ENSMMUP00000039564	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	Proteasome 26S subunit, non-ATPase 6.	0.998
PSMD1	SHPK	ENSMMUP00000015459	ENSMMUP00000030791	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	FGGY_N domain-containing protein.	0.708
PSMD11	PSMB4	ENSMMUP00000073478	ENSMMUP00000027532	Proteasome 26S subunit, non-ATPase 11.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.997
PSMD11	PSMD1	ENSMMUP00000073478	ENSMMUP00000015459	Proteasome 26S subunit, non-ATPase 11.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.999