STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM28ADAM metallopeptidase domain 28. (790 aa)    
Predicted Functional Partners:
LGI1
Leucine-rich glioma-inactivated protein 1.
    
 0.780
CNBD1
Cyclic nucleotide binding domain containing 1.
      
 0.640
ADAM22
ADAM metallopeptidase domain 22.
    
 
0.597
STK38L
Non-specific serine/threonine protein kinase.
      
 0.594
ZFYVE1
Zinc finger FYVE domain-containing protein 1 isoform 1.
      
 0.592
TSC22D1
TSC22 domain family member 1.
    
 
 0.553
MANEA
Glycoprotein endo-alpha-1,2-mannosidase.
   
 0.539
RPL15
Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.
      
 0.539
USP33
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
      
 0.538
TMEFF2
Transmembrane protein with EGF like and two follistatin like domains 2.
    
 
 0.535
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.