Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGRP | ASIP | ENSMMUP00000071178 | ENSMMUP00000077604 | Agouti related neuropeptide. | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | 0.599 |
| AGRP | MC1R | ENSMMUP00000071178 | ENSMMUP00000032257 | Agouti related neuropeptide. | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). | 0.575 |
| AGRP | POMC | ENSMMUP00000071178 | ENSMMUP00000075833 | Agouti related neuropeptide. | Uncharacterized protein. | 0.967 |
| ASIP | AGRP | ENSMMUP00000077604 | ENSMMUP00000071178 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Agouti related neuropeptide. | 0.599 |
| ASIP | ATRN | ENSMMUP00000077604 | ENSMMUP00000029334 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Attractin isoform 1 preproprotein. | 0.678 |
| ASIP | MC1R | ENSMMUP00000077604 | ENSMMUP00000032257 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). | 0.939 |
| ASIP | MITF | ENSMMUP00000077604 | ENSMMUP00000056527 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Microphthalmia-associated transcription factor isoform 1. | 0.654 |
| ASIP | OCA2 | ENSMMUP00000077604 | ENSMMUP00000015778 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | OCA2 melanosomal transmembrane protein. | 0.715 |
| ASIP | POMC | ENSMMUP00000077604 | ENSMMUP00000075833 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Uncharacterized protein. | 0.524 |
| ASIP | SLC24A5 | ENSMMUP00000077604 | ENSMMUP00000024781 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. | 0.654 |
| ASIP | SLC45A2 | ENSMMUP00000077604 | ENSMMUP00000034889 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Solute carrier family 45 member 2. | 0.700 |
| ASIP | TYR | ENSMMUP00000077604 | ENSMMUP00000014548 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Tyrosinase. | 0.728 |
| ASIP | TYRP1 | ENSMMUP00000077604 | ENSMMUP00000071668 | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | Tyrosinase related protein 1. | 0.738 |
| ATRN | ASIP | ENSMMUP00000029334 | ENSMMUP00000077604 | Attractin isoform 1 preproprotein. | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | 0.678 |
| ATRN | MC1R | ENSMMUP00000029334 | ENSMMUP00000032257 | Attractin isoform 1 preproprotein. | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). | 0.647 |
| MC1R | AGRP | ENSMMUP00000032257 | ENSMMUP00000071178 | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). | Agouti related neuropeptide. | 0.575 |
| MC1R | ASIP | ENSMMUP00000032257 | ENSMMUP00000077604 | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). | Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). | 0.939 |
| MC1R | ATRN | ENSMMUP00000032257 | ENSMMUP00000029334 | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). | Attractin isoform 1 preproprotein. | 0.647 |
| MC1R | MITF | ENSMMUP00000032257 | ENSMMUP00000056527 | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). | Microphthalmia-associated transcription factor isoform 1. | 0.742 |
| MC1R | OCA2 | ENSMMUP00000032257 | ENSMMUP00000015778 | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). | OCA2 melanosomal transmembrane protein. | 0.742 |
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