STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPIRE2Spire type actin nucleation factor 2. (714 aa)    
Predicted Functional Partners:
GRAP2
GRB2 related adaptor protein 2.
   
 0.822
MYO5A
Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.800
RIMBP2
RIMS binding protein 2.
      
 0.747
GRB2
Growth factor receptor-bound protein 2 isoform 1.
   
 0.743
FMN2
Formin 2.
    
 0.726
FMN1
Formin 1.
    
 0.687
SLC28A3
Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
      
 0.685
SIK3
SIK family kinase 3.
   
 0.662
ILDR1
Ig-like domain-containing protein.
    
 0.653
ARSG
Arylsulfatase G.
    
 0.627
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.