Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANK3Ankyrin 3. (4375 aa)    
Predicted Functional Partners:
ERBB4
Receptor protein-tyrosine kinase.
   
 0.975
ANK2
Ankyrin 2.
   
 
0.942
CD44
Phagocytic glycoprotein I.
   
 
 0.936
ANK1
Ankyrin 1.
     
0.918
TIAM1
Uncharacterized protein.
    
 0.916
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1 isoform 3.
   
 0.914
NFASC
Neurofascin.
   
 0.907
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
    
 0.906
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3.
    
 0.906
F7H9V3_MACMU
Uncharacterized protein.
   
 0.856
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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