| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCAR2 | SIRT1 | ENSMMUP00000076070 | ENSMMUP00000035809 | P30 DBC protein. | Sirtuin 1. | 0.998 |
| FOXO1 | FOXO3 | ENSMMUP00000036378 | ENSMMUP00000032969 | Forkhead box O1. | Forkhead box O3. | 0.976 |
| FOXO1 | NAMPT | ENSMMUP00000036378 | ENSMMUP00000060788 | Forkhead box O1. | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | 0.401 |
| FOXO1 | PPARG | ENSMMUP00000036378 | ENSMMUP00000076208 | Forkhead box O1. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.768 |
| FOXO1 | PPARGC1A | ENSMMUP00000036378 | ENSMMUP00000060440 | Forkhead box O1. | PPARG coactivator 1 alpha. | 0.992 |
| FOXO1 | SIRT1 | ENSMMUP00000036378 | ENSMMUP00000035809 | Forkhead box O1. | Sirtuin 1. | 0.998 |
| FOXO1 | SIRT6 | ENSMMUP00000036378 | ENSMMUP00000026241 | Forkhead box O1. | NAD-dependent deacetylase sirtuin-6. | 0.752 |
| FOXO1 | SIRT7 | ENSMMUP00000036378 | ENSMMUP00000061375 | Forkhead box O1. | Sirtuin 7. | 0.630 |
| FOXO1 | TP53 | ENSMMUP00000036378 | ENSMMUP00000011334 | Forkhead box O1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.878 |
| FOXO3 | FOXO1 | ENSMMUP00000032969 | ENSMMUP00000036378 | Forkhead box O3. | Forkhead box O1. | 0.976 |
| FOXO3 | PPARG | ENSMMUP00000032969 | ENSMMUP00000076208 | Forkhead box O3. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.598 |
| FOXO3 | PPARGC1A | ENSMMUP00000032969 | ENSMMUP00000060440 | Forkhead box O3. | PPARG coactivator 1 alpha. | 0.793 |
| FOXO3 | SIRT1 | ENSMMUP00000032969 | ENSMMUP00000035809 | Forkhead box O3. | Sirtuin 1. | 0.997 |
| FOXO3 | SIRT6 | ENSMMUP00000032969 | ENSMMUP00000026241 | Forkhead box O3. | NAD-dependent deacetylase sirtuin-6. | 0.701 |
| FOXO3 | SIRT7 | ENSMMUP00000032969 | ENSMMUP00000061375 | Forkhead box O3. | Sirtuin 7. | 0.530 |
| FOXO3 | TP53 | ENSMMUP00000032969 | ENSMMUP00000011334 | Forkhead box O3. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.915 |
| NAMPT | FOXO1 | ENSMMUP00000060788 | ENSMMUP00000036378 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | Forkhead box O1. | 0.401 |
| NAMPT | PPARG | ENSMMUP00000060788 | ENSMMUP00000076208 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.499 |
| NAMPT | PPARGC1A | ENSMMUP00000060788 | ENSMMUP00000060440 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | PPARG coactivator 1 alpha. | 0.410 |
| NAMPT | SIRT1 | ENSMMUP00000060788 | ENSMMUP00000035809 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | Sirtuin 1. | 0.985 |
